TNFAIP1 Antikörper
Kurzübersicht für TNFAIP1 Antikörper (ABIN7120411)
Target
Alle TNFAIP1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Verwendungszweck
- TNFAIP1 antibody
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Aufreinigung
- Protein A+G purification
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Reinheit
- ≥95 % as determined by SDS-PAGE
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Immunogen
- tumor necrosis factor, alpha-induced protein 1(endothelial)
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Isotyp
- IgG1
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Applikationshinweise
- WB: 1:1000-1:6000, IHC: 1:50-1:600
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze / thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- -20°C for 12 months
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Haltbarkeit
- 12 months
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- TNFAIP1 (Tumor Necrosis Factor, alpha-Induced Protein 1 (Endothelial) (TNFAIP1))
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Andere Bezeichnung
- TNFAIP1
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Hintergrund
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Synonyms: BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2 (hBACURD2)|BTB/POZ domain-containing protein TNFAIP1|Protein B12|Tumor necrosis factor, alpha-induced protein 1, endothelial|TNFAIP1|BACURD2|EDP1
Background: Substrate-specific adapter of a BCR(BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex involved in regulation of cytoskeleton structure. The BCR(BACURD2) E3 ubiquitin ligase complex mediates the ubiquitination of RHOA, leading to its degradation by the proteasome, thereby regulating the actin cytoskeleton and cell migration. Its interaction with RHOB may regulate apoptosis. May enhance the PCNA-dependent DNA polymerase delta activity.
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Molekulargewicht
- 36 kDa
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Gen-ID
- 7126
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UniProt
- Q13829
Target
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