TMPRSS2 Antikörper (AA 110-360)

Produktnummer ABIN7120185

Dieses Anti-TMPRSS2-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von TMPRSS2 in WB, IHC und ELISA. Geeignet für Human, Maus und Ratte.

Kurzübersicht für TMPRSS2 Antikörper (AA 110-360) (ABIN7120185)

Target: TMPRSS2 (Transmembrane Protease, serine 2 (TMPRSS2))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TMPRSS2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Produktdetails anti-TMPRSS2 Antikörper

Bindungsspezifität: AA 110-360

Verwendungszweck: TMPRSS2 antibody

Aufreinigung: Immunogen affinity purified

Reinheit: ≥95 % as determined by SDS-PAGE

Immunogen:

Immunogen sequence: 110-360aa,extra-cellular domain

Immunogen: transmembrane protease, serine 2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C for 12 months

Haltbarkeit: 12 months

Details zu TMPRSS2

Target: TMPRSS2 (Transmembrane Protease, serine 2 (TMPRSS2))

Andere Bezeichnung: TMPRSS2

Hintergrund:

Synonyms: Transmembrane protease serine 2|Serine protease 10|Transmembrane protease serine 2 non-catalytic chain|Transmembrane protease serine 2 catalytic chain|TMPRSS2|PRSS10

Background: This gene encodes a protein that belongs to the serine protease family. The encoded protein contains a type II transmembrane domain, a receptor class A domain, a scavenger receptor cysteine-rich domain and a protease domain. Serine proteases are known to be involved in many physiological and pathological processes. This gene was demonstrated to be up-regulated by androgenic hormones in prostate cancer cells and down-regulated in androgen-independent prostate cancer tissue. The protease domain of this protein is thought to be cleaved and secreted into cell media after autocleavage. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Molekulargewicht: 52 kDa

Gen-ID: 7113

UniProt: O15393

Pathways: SARS-CoV-2 Protein Interaktom