TFB2M Antikörper
Kurzübersicht für TFB2M Antikörper (ABIN7120070)
Target
Alle TFB2M Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Verwendungszweck
- TFB2M antibody
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Aufreinigung
- Immunogen affinity purified
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Reinheit
- ≥95 % as determined by SDS-PAGE
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Immunogen
- transcription factor B2, mitochondrial
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Isotyp
- IgG
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Applikationshinweise
- WB: 1:500-1:2000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze / thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- -20°C for 12 months
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Haltbarkeit
- 12 months
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- TFB2M (Transcription Factor B2, Mitochondrial (TFB2M))
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Andere Bezeichnung
- TFB2M
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Hintergrund
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Synonyms: Dimethyladenosine transferase 2, mitochondrial|Hepatitis C virus NS5A-transactivated protein 5 (HCV NS5A-transactivated protein 5)|Mitochondrial 12S rRNA dimethylase 2|Mitochondrial transcription factor B2 (h-mtTFB, h-mtTFB2, hTFB2M, mtTFB2)|S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase 2|TFB2M|NS5ATP5
Background: S-adenosyl-L-methionine-dependent methyltransferase which specifically dimethylates mitochondrial 12S rRNA at the conserved stem loop. Also required for basal transcription of mitochondrial DNA, probably via its interaction with POLRMT and TFAM. Stimulates transcription independently of the methyltransferase activity. Compared to TFB1M, it activates transcription of mitochondrial DNA more efficiently, while it has less methyltransferase activity.
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Molekulargewicht
- 45-50 kDa
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Gen-ID
- 64216
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UniProt
- Q9H5Q4
Target
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