TPX2 Antikörper
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- Target Alle TPX2 Antikörper anzeigen
- TPX2 (TPX2, Microtubule-Associated, Homolog (Xenopus Laevis) (TPX2))
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser TPX2 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunoprecipitation (IP), Immunofluorescence (IF)
- Aufreinigung
- Immunogen affinity purified
- Reinheit
- ≥95 % as determined by SDS-PAGE
- Immunogen
- TPX2, microtubule-associated, homolog(Xenopus laevis)
- Isotyp
- IgG
- Top Product
- Discover our top product TPX2 Primärantikörper
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anti-TPX2, Microtubule-Associated, Homolog (Xenopus Laevis) (TPX2) antibody
TPX2 Reaktivität: Human, Maus, Ratte WB, ELISA, IP, IHC (p), ICC Wirt: Maus Monoclonal TPX2-01 unconjugated
anti-TPX2, Microtubule-Associated, Homolog (Xenopus Laevis) (TPX2) (C-Term) antibodyTPX2 Reaktivität: Human, Maus, Ratte WB, ELISA, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-TPX2, Microtubule-Associated, Homolog (Xenopus Laevis) (TPX2) antibodyTPX2 Reaktivität: Human WB, IP, ICC, FACS, DB Wirt: Maus Monoclonal 3164C6a unconjugated
anti-TPX2, Microtubule-Associated, Homolog (Xenopus Laevis) (TPX2) (AA 160-320) antibodyTPX2 Reaktivität: Human WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-TPX2, Microtubule-Associated, Homolog (Xenopus Laevis) (TPX2) (AA 350-382) antibodyTPX2 Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal RB0559 unconjugated
anti-TPX2, Microtubule-Associated, Homolog (Xenopus Laevis) (TPX2) antibodyTPX2 Reaktivität: Human, Maus WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-TPX2, Microtubule-Associated, Homolog (Xenopus Laevis) (TPX2) (AA 1-220) antibodyTPX2 Reaktivität: Human WB, IHC, IHC (p) Wirt: Maus Monoclonal 18D5 unconjugated
anti-TPX2, Microtubule-Associated, Homolog (Xenopus Laevis) (TPX2) (C-Term) antibodyTPX2 Reaktivität: Human, Maus, Ratte, Meerschweinchen, Rind (Kuh), Hund, Pferd, Kaninchen WB Wirt: Kaninchen Polyclonal unconjugated
anti-TPX2, Microtubule-Associated, Homolog (Xenopus Laevis) (TPX2) (Internal Region) antibodyTPX2 Reaktivität: Human, Maus WB, IHC (p), EIA Wirt: Kaninchen Polyclonal unconjugated
anti-TPX2, Microtubule-Associated, Homolog (Xenopus Laevis) (TPX2) (AA 551-650) antibodyTPX2 Reaktivität: Maus WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
- WB: 1:500-1:2000, IP: 1:200-1:1000, IF: 1:20-1:200
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
- Haltbarkeit
- 12 months
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- Target
- TPX2 (TPX2, Microtubule-Associated, Homolog (Xenopus Laevis) (TPX2))
- Andere Bezeichnung
- TPX2 (TPX2 Produkte)
- Hintergrund
- Synonyms:C20orf1, C20orf2, DIL2, HCA519 Background:Spindle assembly factor required for normal assembly of mitotic spindles. Required for normal assembly of microtubules during apoptosis. Required for chromatin and/or kinetochore dependent microtubule nucleation. Mediates AURKA localization to spindle microtubules(PubMed:18663142, PubMed:19208764). Activates AURKA by promoting its autophosphorylation at 'Thr-288' and protects this residue against dephosphorylation(PubMed:18663142, PubMed:19208764). TPX2 is inactivated upon binding to importin-alpha(PubMed:26165940). At the onset of mitosis, GOLGA2 interacts with importin-alpha, liberating TPX2 from importin-alpha, allowing TPX2 to activates AURKA kinase and stimulates local microtubule nucleation(PubMed:26165940).
- Molekulargewicht
- 100 kDa
- UniProt
- Q9ULW0
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