TRIAP1 Antikörper

Produktnummer ABIN7120027

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch TRIAP1 in WB und ELISA. Er zeigt eine Reaktivität gegenüber Human, Maus und Ratte.

Kurzübersicht für TRIAP1 Antikörper (ABIN7120027)

Target: TRIAP1 (TP53 Regulated Inhibitor of Apoptosis 1 (TRIAP1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TRIAP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-TRIAP1 Antikörper

Verwendungszweck: TRIAP1 antibody

Aufreinigung: Immunogen affinity purified

Reinheit: ≥95 % as determined by SDS-PAGE

Immunogen: TP53 regulated inhibitor of apoptosis 1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:5000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C for 12 months

Haltbarkeit: 12 months

Details zu TRIAP1

Target: TRIAP1 (TP53 Regulated Inhibitor of Apoptosis 1 (TRIAP1))

Andere Bezeichnung: TRIAP1

Hintergrund:

Synonyms: TP53-regulated inhibitor of apoptosis 1|Protein 15E1.1|WF-1|p53-inducible cell-survival factor (p53CSV)|TRIAP1|15E1.1

Background: Involved in the modulation of the mitochondrial apoptotic pathway by ensuring the accumulation of cardiolipin(CL) in mitochondrial membranes. In vitro, the TRIAP1:PRELID1 complex mediates the transfer of phosphatidic acid(PA) between liposomes and probably functions as a PA transporter across the mitochondrion intermembrane space to provide PA for CL synthesis in the inner membrane(PubMed:23931759). Likewise, the TRIAP1:PRELID3A complex mediates the transfer of phosphatidic acid(PA) between liposomes(in vitro) and probably functions as a PA transporter across the mitochondrion intermembrane space(in vivo)(PubMed:26071602). Mediates cell survival by inhibiting activation of caspase-9 which prevents induction of apoptosis(PubMed:15735003).

Molekulargewicht: 32 kDa

Gen-ID: 51499

UniProt: O43715

Pathways: Negative Regulation of intrinsic apoptotic Signaling