TRIAP1 Antikörper

Produktnummer ABIN7120027

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch TRIAP1 in ELISA und WB. Es zeigt Reaktivität gegenüber Proben von Human, Maus und Ratte.

Kurzübersicht für TRIAP1 Antikörper (ABIN7120027)

Target: TRIAP1 (TP53 Regulated Inhibitor of Apoptosis 1 (TRIAP1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TRIAP1 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB)

Produktdetails anti-TRIAP1 Antikörper

Verwendungszweck: TRIAP1 antibody

Aufreinigung: Immunogen affinity purified

Reinheit: ≥95 % as determined by SDS-PAGE

Immunogen: TP53 regulated inhibitor of apoptosis 1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:5000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C for 12 months

Haltbarkeit: 12 months

Details zu TRIAP1

Target: TRIAP1 (TP53 Regulated Inhibitor of Apoptosis 1 (TRIAP1))

Andere Bezeichnung: TRIAP1

Hintergrund:

Synonyms: TP53-regulated inhibitor of apoptosis 1|Protein 15E1.1|WF-1|p53-inducible cell-survival factor (p53CSV)|TRIAP1|15E1.1

Background: Involved in the modulation of the mitochondrial apoptotic pathway by ensuring the accumulation of cardiolipin(CL) in mitochondrial membranes. In vitro, the TRIAP1:PRELID1 complex mediates the transfer of phosphatidic acid(PA) between liposomes and probably functions as a PA transporter across the mitochondrion intermembrane space to provide PA for CL synthesis in the inner membrane(PubMed:23931759). Likewise, the TRIAP1:PRELID3A complex mediates the transfer of phosphatidic acid(PA) between liposomes(in vitro) and probably functions as a PA transporter across the mitochondrion intermembrane space(in vivo)(PubMed:26071602). Mediates cell survival by inhibiting activation of caspase-9 which prevents induction of apoptosis(PubMed:15735003).

Molekulargewicht: 32 kDa

Gen-ID: 51499

UniProt: O43715

Pathways: Negative Regulation of intrinsic apoptotic Signaling