TRAF3IP1 Antikörper

Produktnummer ABIN7119988

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch TRAF3IP1 in WB, ELISA, IHC, IF und IP. Er zeigt eine Reaktivität gegenüber Human, Maus und Ratte.

Kurzübersicht für TRAF3IP1 Antikörper (ABIN7119988)

Target: TRAF3IP1 (TNF Receptor-Associated Factor 3 Interacting Protein 1 (TRAF3IP1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TRAF3IP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)

Produktdetails anti-TRAF3IP1 Antikörper

Verwendungszweck: TRAF3IP1 antibody

Aufreinigung: Immunogen affinity purified

Reinheit: ≥95 % as determined by SDS-PAGE

Immunogen: TNF receptor-associated factor 3 interacting protein 1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:2000, IP: 1:200-1:1000, IHC: 1:20-1:200, IF: 1:20-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C for 12 months

Haltbarkeit: 12 months

Details zu TRAF3IP1

Target: TRAF3IP1 (TNF Receptor-Associated Factor 3 Interacting Protein 1 (TRAF3IP1))

Andere Bezeichnung: TRAF3IP1

Hintergrund:

Synonyms: TRAF3-interacting protein 1|Interleukin-13 receptor alpha 1-binding protein 1|Intraflagellar transport protein 54 homolog|Microtubule-interacting protein associated with TRAF3 (MIP-T3)|TRAF3IP1|IFT54|MIPT3

Background: Plays an inhibitory role on IL13 signaling by binding to IL13RA1. Involved in suppression of IL13-induced STAT6 phosphorylation, transcriptional activity and DNA-binding. Recruits TRAF3 and DISC1 to the microtubules. Involved in kidney development and epithelial morphogenesis. Involved in the regulation of microtubule cytoskeleton organization. Is a negative regulator of microtubule stability, acting through the control of MAP4 levels(PubMed:26487268). Involved in ciliogenesis(By similarity).

Molekulargewicht: 83 kDa

Gen-ID: 26146

UniProt: Q8TDR0

Pathways: Hedgehog Signalweg