TRAF3IP1 Antikörper

Produktnummer ABIN7119988

Dieser Kaninchen Polyklonal Antikörper erkennt spezifisch TRAF3IP1 in WB, ELISA, IHC, IF und IP. Er zeigt eine Reaktivität gegenüber Human, Maus und Ratte.

Kurzübersicht für TRAF3IP1 Antikörper (ABIN7119988)

Target: TRAF3IP1 (TNF Receptor-Associated Factor 3 Interacting Protein 1 (TRAF3IP1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TRAF3IP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)

Produktdetails anti-TRAF3IP1 Antikörper

Verwendungszweck: TRAF3IP1 antibody

Aufreinigung: Immunogen affinity purified

Reinheit: ≥95 % as determined by SDS-PAGE

Immunogen: TNF receptor-associated factor 3 interacting protein 1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:2000, IP: 1:200-1:1000, IHC: 1:20-1:200, IF: 1:20-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C for 12 months

Haltbarkeit: 12 months

Details zu TRAF3IP1

Target: TRAF3IP1 (TNF Receptor-Associated Factor 3 Interacting Protein 1 (TRAF3IP1))

Andere Bezeichnung: TRAF3IP1

Hintergrund:

Synonyms: TRAF3-interacting protein 1|Interleukin-13 receptor alpha 1-binding protein 1|Intraflagellar transport protein 54 homolog|Microtubule-interacting protein associated with TRAF3 (MIP-T3)|TRAF3IP1|IFT54|MIPT3

Background: Plays an inhibitory role on IL13 signaling by binding to IL13RA1. Involved in suppression of IL13-induced STAT6 phosphorylation, transcriptional activity and DNA-binding. Recruits TRAF3 and DISC1 to the microtubules. Involved in kidney development and epithelial morphogenesis. Involved in the regulation of microtubule cytoskeleton organization. Is a negative regulator of microtubule stability, acting through the control of MAP4 levels(PubMed:26487268). Involved in ciliogenesis(By similarity).

Molekulargewicht: 83 kDa

Gen-ID: 26146

UniProt: Q8TDR0

Pathways: Hedgehog Signalweg