Der Kaninchen Polyklonal Anti-TRIP13-Antikörper wurde für WB, ELISA, IHC und IP validiert. Er ist geeignet, TRIP13 in Proben von Human, Maus und Ratte zu detektieren.
Synonyms:16E1 BP, 16E1BP, PCH2, TR interacting protein 13, TRIP 13, TRIP13 Background:Plays a key role in chromosome recombination and chromosome structure development during meiosis. Required at early steps in meiotic recombination that leads to non-crossovers pathways. Also needed for efficient completion of homologous synapsis by influencing crossover distribution along the chromosomes affecting both crossovers and non-crossovers pathways. Also required for development of higher-order chromosome structures and is needed for synaptonemal-complex formation. In males, required for efficient synapsis of the sex chromosomes and for sex body formation. Promotes early steps of the DNA double-strand breaks(DSBs) repair process upstream of the assembly of RAD51 complexes. Required for depletion of HORMAD1 and HORMAD2 from synapsed chromosomes(By similarity).