TTI1 Antikörper
Kurzübersicht für TTI1 Antikörper (ABIN7119826)
Target
Alle TTI1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Verwendungszweck
- TTI1 antibody
-
Aufreinigung
- Immunogen affinity purified
-
Reinheit
- ≥95 % as determined by SDS-PAGE
-
Immunogen
- KIAA0406
-
Isotyp
- IgG
-
-
-
-
Applikationshinweise
- WB: 1:500-1:5000, IP: 1:500-1:5000
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Handhabung
- Avoid repeated freeze / thaw cycles.
-
Lagerung
- -20 °C
-
Informationen zur Lagerung
- -20°C for 12 months
-
Haltbarkeit
- 12 months
-
-
- TTI1 (TELO2 Interacting Protein 1 (TTI1))
-
Andere Bezeichnung
- TTI1
-
Hintergrund
-
Synonyms: TELO2-interacting protein 1 homolog|Protein SMG10|TTI1|KIAA0406|SMG10
Background: Regulator of the DNA damage response(DDR). Part of the TTT complex that is required to stabilize protein levels of the phosphatidylinositol 3-kinase-related protein kinase(PIKK) family proteins. The TTT complex is involved in the cellular resistance to DNA damage stresses, like ionizing radiation(IR), ultraviolet(UV) and mitomycin C(MMC). Together with the TTT complex and HSP90 may participate in the proper folding of newly synthesized PIKKs. Promotes assembly, stabilizes and maintains the activity of mTORC1 and mTORC2 complexes, which regulate cell growth and survival in response to nutrient and hormonal signals.
-
Molekulargewicht
- 122 kDa
-
Gen-ID
- 9675
-
UniProt
- O43156
Target
-