Der Kaninchen Polyklonal Anti-SYTL2-Antikörper wurde für WB, IHC und ELISA validiert. Er ist geeignet, SYTL2 in Proben von Human, Maus und Ratte zu detektieren.
PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C
Informationen zur Lagerung
-20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Haltbarkeit
12 months
Target
SYTL2
(Synaptotagmin Like Protein 2 (SYTL2))
Andere Bezeichnung
SYTL2
Hintergrund
Synonyms:KIAA1597, SGA72M, SLP2, SLP2A Background:Isoform 1 acts as a RAB27A effector protein and plays a role in cytotoxic granule exocytosis in lymphocytes. It is required for cytotoxic granule docking at the immunologic synapse. Isoform 4 binds phosphatidylserine(PS) and phosphatidylinositol-4,5-bisphosphate(PIP2) and promotes the recruitment of glucagon-containing granules to the cell membrane in pancreatic alpha cells. Binding to PS is inhibited by Ca(2+) while binding to PIP2 is Ca(2+) insensitive.