SYNGAP1 Antikörper

Produktnummer ABIN7119648

Dieses Anti-SYNGAP1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von SYNGAP1 in WB, ELISA und IF. Geeignet für Human, Maus und Ratte.

Kurzübersicht für SYNGAP1 Antikörper (ABIN7119648)

Target: SYNGAP1 (Synaptic Ras GTPase Activating Protein 1 (SYNGAP1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SYNGAP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Produktdetails anti-SYNGAP1 Antikörper

Verwendungszweck: SYNGAP1 antibody

Aufreinigung: Immunogen affinity purified

Reinheit: ≥95 % as determined by SDS-PAGE

Immunogen: synaptic Ras GTPase activating protein 1 homolog(rat)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:2000, IF: 1:20-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C for 12 months

Haltbarkeit: 12 months

Details zu SYNGAP1

Target: SYNGAP1 (Synaptic Ras GTPase Activating Protein 1 (SYNGAP1))

Andere Bezeichnung: SYNGAP1

Hintergrund:

Synonyms: Ras/Rap GTPase-activating protein SynGAP|Neuronal RasGAP|Synaptic Ras GTPase-activating protein 1 (Synaptic Ras-GAP 1)|SYNGAP1|KIAA1938

Background: Major constituent of the PSD essential for postsynaptic signaling. Inhibitory regulator of the Ras-cAMP pathway. Member of the NMDAR signaling complex in excitatory synapses, it may play a role in NMDAR-dependent control of AMPAR potentiation, AMPAR membrane trafficking and synaptic plasticity. Regulates AMPAR-mediated miniature excitatory postsynaptic currents. Exhibits dual GTPase-activating specificity for Ras and Rap. May be involved in certain forms of brain injury, leading to long-term learning and memory deficits(By similarity).

Molekulargewicht: 148 kDa

Gen-ID: 8831

UniProt: Q96PV0

Pathways: Regulation of long-term Neuronal Synaptic Plasticity