Stim2 Antikörper
Kurzübersicht für Stim2 Antikörper (ABIN7119555)
Target
Alle Stim2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Verwendungszweck
- STIM2 antibody
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Aufreinigung
- Immunogen affinity purified
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Reinheit
- ≥95 % as determined by SDS-PAGE
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Immunogen
- stromal interaction molecule 2
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Isotyp
- IgG
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Applikationshinweise
- WB: 1:500-1:2000, IP: 1:200-1:1000, IHC: 1:20-1:200
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze / thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- -20°C for 12 months
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Haltbarkeit
- 12 months
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- Stim2 (Stromal Interaction Molecule 2 (Stim2))
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Andere Bezeichnung
- STIM2
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Hintergrund
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Synonyms: Stromal interaction molecule 2|STIM2|KIAA1482
Background: Plays a role in mediating store-operated Ca(2+) entry(SOCE), a Ca(2+) influx following depletion of intracellular Ca(2+) stores. Functions as a highly sensitive Ca(2+) sensor in the endoplasmic reticulum which activates both store-operated and store-independent Ca(2+)-influx. Regulates basal cytosolic and endoplasmic reticulum Ca(2+) concentrations. Upon mild variations of the endoplasmic reticulum Ca(2+) concentration, translocates from the endoplasmic reticulum to the plasma membrane where it probably activates the Ca(2+) release-activated Ca(2+)(CRAC) channels ORAI1, ORAI2 and ORAI3. May inhibit STIM1-mediated Ca(2+) influx.
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Molekulargewicht
- 85-115 kDa
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Gen-ID
- 57620
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UniProt
- Q9P246
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Pathways
- T-Zell Rezeptor Signalweg, BCR Signaling
Target
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