SNX17 Antikörper

Produktnummer ABIN7119355

Produktdetails anti-SNX17 Antikörper

Target: SNX17 (Sorting Nexin 17 (SNX17))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SNX17 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunofluorescence (IF)

Aufreinigung: Immunogen affinity purified

Reinheit: ≥95 % as determined by SDS-PAGE

Immunogen: sorting nexin 17

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:2000, IP: 1:500-1:2000, IHC: 1:50-1:200, IF: 1:20-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Haltbarkeit: 12 months

Details zu SNX17

Target: SNX17 (Sorting Nexin 17 (SNX17))

Andere Bezeichnung: SNX17 (SNX17 Produkte)

Synonyme: snx17 antikoerper, MGC53167 antikoerper, MGC69341 antikoerper, MGC198061 antikoerper, MGC83142 antikoerper, SNX17 antikoerper, wu:fb67g03 antikoerper, wu:fb67g09 antikoerper, wu:fc27g08 antikoerper, wu:fj81d04 antikoerper, si:ch211-101l18.2 antikoerper, 5830447M19Rik antikoerper, AI790646 antikoerper, D5Ertd260e antikoerper, mKIAA0064 antikoerper, sorting nexin 17 antikoerper, sorting nexin 17 L homeolog antikoerper, snx17 antikoerper, SNX17 antikoerper, snx17.L antikoerper, Snx17 antikoerper

Hintergrund: Synonyms:KIAA0064 Background:Critical regulator of endosomal recycling of numerous receptors, channels, and other transmembrane proteins. Binds to NPxY sequences in the cytoplasmic tails of target cargos. Plays a role in the sorting of endocytosed LRP1 and APP, and prevents their degradation. Required for maintenance of normal cell surface levels of APP and LRP1. Recycles internalized integrins ITGB1, ITGB5 and their associated alpha subunits, preventing them from lysosomal degradation. Interacts with membranes containing phosphatidylinositol 3-phosphate(PtdIns(3P)).

Molekulargewicht: 52 kDa

Gen-ID: 9784

UniProt: Q15036