SNX17 Antikörper (N-Term)

Produktnummer ABIN6265212

Produktdetails anti-SNX17 Antikörper

Target: SNX17 (Sorting Nexin 17 (SNX17))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SNX17 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Spezifität: SNX17 Antibody detects endogenous levels of total SNX17.

Homologie: Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Xenopus

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human SNX17, corresponding to a region within N-terminal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu SNX17

Target: SNX17 (Sorting Nexin 17 (SNX17))

Andere Bezeichnung: SNX17 (SNX17 Produkte)

Synonyme: snx17 antikoerper, MGC53167 antikoerper, MGC69341 antikoerper, MGC198061 antikoerper, MGC83142 antikoerper, SNX17 antikoerper, wu:fb67g03 antikoerper, wu:fb67g09 antikoerper, wu:fc27g08 antikoerper, wu:fj81d04 antikoerper, si:ch211-101l18.2 antikoerper, 5830447M19Rik antikoerper, AI790646 antikoerper, D5Ertd260e antikoerper, mKIAA0064 antikoerper, sorting nexin 17 antikoerper, sorting nexin 17 L homeolog antikoerper, snx17 antikoerper, SNX17 antikoerper, snx17.L antikoerper, Snx17 antikoerper

Hintergrund:

Description: Critical regulator of endosomal recycling of numerous receptors, channels, and other transmembrane proteins. Binds to NPxY sequences in the cytoplasmic tails of target cargos. Plays a role in the sorting of endocytosed LRP1 and APP, and prevents their degradation. Required for maintenance of normal cell surface levels of APP and LRP1. Recycles internalized integrins ITGB1, ITGB5 and their associated alpha subunits, preventing them from lysosomal degradation. Interacts with membranes containing phosphatidylinositol 3-phosphate (PtdIns(3P)).

Gene: SNX17

Molekulargewicht: 50 kDa

Gen-ID: 9784

UniProt: Q15036