SNX17 Antikörper
Kurzübersicht für SNX17 Antikörper (ABIN7119355)
Target
Alle SNX17 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Verwendungszweck
- SNX17 antibody
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Aufreinigung
- Immunogen affinity purified
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Reinheit
- ≥95 % as determined by SDS-PAGE
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Immunogen
- sorting nexin 17
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Isotyp
- IgG
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Applikationshinweise
- WB: 1:500-1:2000, IP: 1:500-1:2000, IHC: 1:50-1:200, IF: 1:20-1:200
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze / thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- -20°C for 12 months
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Haltbarkeit
- 12 months
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- SNX17 (Sorting Nexin 17 (SNX17))
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Andere Bezeichnung
- SNX17
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Hintergrund
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Synonyms: Sorting nexin-17|SNX17|KIAA0064
Background: Critical regulator of endosomal recycling of numerous receptors, channels, and other transmembrane proteins. Binds to NPxY sequences in the cytoplasmic tails of target cargos. Plays a role in the sorting of endocytosed LRP1 and APP, and prevents their degradation. Required for maintenance of normal cell surface levels of APP and LRP1. Recycles internalized integrins ITGB1, ITGB5 and their associated alpha subunits, preventing them from lysosomal degradation. Interacts with membranes containing phosphatidylinositol 3-phosphate(PtdIns(3P)).
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Molekulargewicht
- 52 kDa
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Gen-ID
- 9784
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UniProt
- Q15036
Target
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