SMCR7L Antikörper

Produktnummer ABIN7119193

Dieser Kaninchen Polyklonal Antikörper erkennt spezifisch SMCR7L in WB, ELISA, IF und IP. Er zeigt eine Reaktivität gegenüber Human, Maus und Ratte.

Kurzübersicht für SMCR7L Antikörper (ABIN7119193)

Target: SMCR7L (Smith-Magenis Syndrome Chromosome Region, Candidate 7-Like (SMCR7L))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SMCR7L Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunoprecipitation (IP)

Produktdetails anti-SMCR7L Antikörper

Verwendungszweck: MIEF1 antibody

Aufreinigung: Immunogen affinity purified

Reinheit: ≥95 % as determined by SDS-PAGE

Immunogen: Smith-Magenis syndrome chromosome region, candidate 7-like

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:5000, IP: 1:500-1:5000, IF: 1:10-1:100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C for 12 months

Haltbarkeit: 12 months

Details zu SMCR7L

Target: SMCR7L (Smith-Magenis Syndrome Chromosome Region, Candidate 7-Like (SMCR7L))

Andere Bezeichnung: MIEF1

Hintergrund:

Synonyms: Mitochondrial dynamics protein MIEF1|Mitochondrial dynamics protein of 51 kDa|Mitochondrial elongation factor 1|Smith-Magenis syndrome chromosomal region candidate gene 7 protein-like (SMCR7-like protein)|MIEF1|MID51|SMCR7L

Background: Human SMCR7L gene encodes, MID51, the mitochondrial dynamic protein of 51 kDa(also called mitochondrial elongation factor 1, MIEF1). MID51 is a single-pass membrane protein anchored to the mitochondrial outer membrane and regulates mitochondrial morphology. Mitochondrial morphology is controlled by two opposing processes: fusion and fission. Elevated MID51 levels induce extensive mitochondrial fusion, whereas depletion of MID51 causes mitochondrial fragmentation. MID51 interacts with and recruits Drp1 to mitochondria, suggesting a critical role of MID51 in regulation of mitochondrial fusion-fission machinery in vertebrates.

Molekulargewicht: 49 kDa

Gen-ID: 54471

UniProt: Q9NQG6