SH3BP4 Antikörper
Kurzübersicht für SH3BP4 Antikörper (ABIN7119024)
Target
Alle SH3BP4 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Aufreinigung
- Immunogen affinity purified
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Reinheit
- ≥95 % as determined by SDS-PAGE
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Immunogen
- SH3-domain binding protein 4
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Isotyp
- IgG
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Applikationshinweise
- WB: 1:500-1:2000, IP: 1:200-1:1000, IF: 1:20-1:200
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
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Haltbarkeit
- 12 months
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- SH3BP4 (SH3-Domain Binding Protein 4 (SH3BP4))
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Andere Bezeichnung
- SH3BP4
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Hintergrund
- Synonyms:BOG25, EHB10, TTP Background:May function in transferrin receptor internalization at the plasma membrane through a cargo-specific control of clathrin-mediated endocytosis. Alternatively, may act as a negative regulator of the amino acid-induced TOR signaling by inhibiting the formation of active Rag GTPase complexes. Preferentially binds inactive Rag GTPase complexes and prevents their interaction with the mTORC1 complex inhibiting its relocalization to lysosomes and its activation. Thereby, may indirectly regulate cell growth, proliferation and autophagy.
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Molekulargewicht
- 120 kDa
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Gen-ID
- 23677
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UniProt
- Q9P0V3
Target
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