SH3BP4 Antikörper

Produktnummer ABIN306590

Der Schaf Polyklonal anti-SH3BP4 Antikörper wird verwendet zum Nachweis von SH3BP4 in Proben von Human. Er wurde validiert für WB.

Kurzübersicht für SH3BP4 Antikörper (ABIN306590)

Target: SH3BP4 (SH3-Domain Binding Protein 4 (SH3BP4))

Reaktivität: Human

Wirt: Schaf

Klonalität: Polyklonal

Konjugat: Dieser SH3BP4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-SH3BP4 Antikörper

Verwendungszweck: Sheep anti Human Guanalyate Kinase GKWW domain (MAGI)

Kreuzreaktivität: Human

Produktmerkmale: Membrane-associated guanylate kinase with inverted orientation (MAGI3) is a novel, 130 kDa guanylate kinase which is part of a family of multi-PDZ domain containing guanylate kinases. These guanylate kinases are localized to epithelial cell tight junctions. MAGI3 and PTEN/MMAC cooperate to modulate the kinase activity of AKT/protein kinase B (PKB). MAGI3 positions the PTEN/MMAC phosphatase to specific subcellular locations that are involved with the regulation of cell proliferation and survival. MAGI3, as well as other proteins in this family, are made up of an N-terminal guanylate kinase domain, followed by a WW domain, named for two conserved tryptophan residues and first identified as two repeats in mouse YAP65, which is then followed by 6 PDZ domains.

Aufreinigung: Ammonium Sulfate Precipitation

Immunogen: Recombinant protein corresponding to the guanylate kinase-WW domain of MAGI-3.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Antibody detects MAGI-3 by Western blot at 1-10 μg/mL. Detects a 130 kDa band in cells transfected with full-length MAGI-3 protein. Optimal concentration should be evaluated by serial dilutions.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: phosphate buffered saline with 0.08 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles

Details zu SH3BP4

Target: SH3BP4 (SH3-Domain Binding Protein 4 (SH3BP4))

Andere Bezeichnung: Membrane AssociatedGuanalyate Kinase GKWW domain (MAGI)

Hintergrund: Sheep anti-Membrane-associated guanylate cyclase of inverted orientation-3, Guanylate Kinase-WW domains

UniProt: Q9H2V6