SH3PXD2A Antikörper (AA 385-533)
Kurzübersicht für SH3PXD2A Antikörper (AA 385-533) (ABIN7119018)
Target
Alle SH3PXD2A Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 385-533
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Verwendungszweck
- SH3PXD2A antibody
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Aufreinigung
- Immunogen affinity purified
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Reinheit
- ≥95 % as determined by SDS-PAGE
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Immunogen
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Immunogen sequence: 385-533aa
Immunogen: SH3 and PX domains 2A
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Isotyp
- IgG
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Applikationshinweise
- WB: 1:500-1:1000, IHC: 1:20-1:200, IF: 1:10-1:100
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze / thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- -20°C for 12 months
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Haltbarkeit
- 12 months
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- SH3PXD2A (SH3 and PX Domains 2A (SH3PXD2A))
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Andere Bezeichnung
- SH3PXD2A
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Hintergrund
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Synonyms: SH3 and PX domain-containing protein 2A|Adapter protein TKS5|Five SH3 domain-containing protein|SH3 multiple domains protein 1|Tyrosine kinase substrate with five SH3 domains|SH3PXD2A|FISH|KIAA0418|SH3MD1|TKS5
Background: Adapter protein involved in invadopodia and podosome formation, extracellular matrix degradation and invasiveness of some cancer cells. Binds matrix metalloproteinases(ADAMs), NADPH oxidases(NOXs) and phosphoinositides. Acts as an organizer protein that allows NOX1-or NOX3-dependent reactive oxygen species(ROS) generation and ROS localization. In association with ADAM12, mediates the neurotoxic effect of beta-amyloid peptide.
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Molekulargewicht
- 140 kDa
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Gen-ID
- 9644
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UniProt
- Q5TCZ1
Target
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