Der Kaninchen Polyklonal Anti-SHMT1-Antikörper wurde für WB, IHC und ELISA validiert. Er ist geeignet, SHMT1 in Proben von Human, Maus und Ratte zu detektieren.
Synonyms: Background:This gene encodes the cytosolic form of serine hydroxymethyltransferase, a pyridoxal phosphate-containing enzyme that catalyzes the reversible conversion of serine and tetrahydrofolate to glycine and 5, 10-methylene tetrahydrofolate. This reaction provides one-carbon units for synthesis of methionine, thymidylate, and purines in the cytoplasm. This gene is located within the Smith-Magenis syndrome region on chromosome 17. A pseudogene of this gene is located on the short arm of chromosome 1. Alternative splicing results in multiple transcript variants.