RBM14 Antikörper

Produktnummer ABIN7118671

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch RBM14 in WB und ELISA. Es zeigt Reaktivität gegenüber Proben von Human, Maus und Ratte.

Kurzübersicht für RBM14 Antikörper (ABIN7118671)

Target: RBM14 (RNA Binding Motif Protein 14 (RBM14))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RBM14 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-RBM14 Antikörper

Verwendungszweck: RBM14 antibody

Aufreinigung: Immunogen affinity purified

Reinheit: ≥95 % as determined by SDS-PAGE

Immunogen: RNA binding motif protein 14

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C for 12 months

Haltbarkeit: 12 months

Details zu RBM14

Target: RBM14 (RNA Binding Motif Protein 14 (RBM14))

Andere Bezeichnung: RBM14

Hintergrund:

Synonyms: RNA-binding protein 14|Paraspeckle protein 2 (PSP2)|RNA-binding motif protein 14|RRM-containing coactivator activator/modulator|Synaptotagmin-interacting protein (SYT-interacting protein)|RBM14|SIP

Background: Isoform 1 may function as a nuclear receptor coactivator, enhancing transcription through other coactivators such as NCOA6 and CITED1. Isoform 2, functions as a transcriptional repressor, modulating transcriptional activities of coactivators including isoform 1, NCOA6 and CITED1(PubMed:11443112). Regulates centriole biogenesis by suppressing the formation of aberrant centriolar protein complexes in the cytoplasm and thus preserving mitotic spindle integrity. Prevents the formation of the STIL-CENPJ complex(which can induce the formation of aberrant centriolar protein complexes) by interfering with the interaction of STIL with CENPJ(PubMed:25385835).

Molekulargewicht: 70-75 kDa

Gen-ID: 10432

UniProt: Q96PK6

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway