ARHGEF7 Antikörper
Kurzübersicht für ARHGEF7 Antikörper (ABIN7118495)
Target
Alle ARHGEF7 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Verwendungszweck
- ARHGEF7 antibody
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Aufreinigung
- Immunogen affinity purified
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Reinheit
- ≥95 % as determined by SDS-PAGE
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Immunogen
- Rho guanine nucleotide exchange factor(GEF) 7
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Isotyp
- IgG
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Applikationshinweise
- WB: 1:1000-1:4000, IP: 1:500-1:2000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze / thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- -20°C for 12 months
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Haltbarkeit
- 12 months
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- ARHGEF7 (rho Guanine Nucleotide Exchange Factor (GEF) 7 (ARHGEF7))
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Andere Bezeichnung
- ARHGEF7
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Hintergrund
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Synonyms: Rho guanine nucleotide exchange factor 7|Beta-Pix|COOL-1|PAK-interacting exchange factor beta|p85|ARHGEF7|COOL1|KIAA0142|P85SPR|PAK3BP|PIXB
Background: Acts as a RAC1 guanine nucleotide exchange factor(GEF) and can induce membrane ruffling. Functions in cell migration, attachment and cell spreading. Promotes targeting of RAC1 to focal adhesions(By similarity). May function as a positive regulator of apoptosis. Downstream of NMDA receptors and CaMKK-CaMK1 signaling cascade, promotes the formation of spines and synapses in hippocampal neurons.
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Molekulargewicht
- 70 kDa
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Gen-ID
- 8874
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UniProt
- Q14155
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Pathways
- EGFR Signaling Pathway, Neurotrophin Signalübertragung, EGFR Downregulation
Target
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