Der Kaninchen Polyklonal Anti-ARHGEF7-Antikörper wurde für WB, ELISA und IP validiert. Er ist geeignet, ARHGEF7 in Proben von Human, Ratte und Maus zu detektieren.
Synonyms:COOL1, KIAA0142, P85SPR, PAK3BP, PIXB Background:Acts as a RAC1 guanine nucleotide exchange factor(GEF) and can induce membrane ruffling. Functions in cell migration, attachment and cell spreading. Promotes targeting of RAC1 to focal adhesions(By similarity). May function as a positive regulator of apoptosis. Downstream of NMDA receptors and CaMKK-CaMK1 signaling cascade, promotes the formation of spines and synapses in hippocampal neurons.