ARHGEF5 Antikörper

Produktnummer ABIN7118494

Produktdetails anti-ARHGEF5 Antikörper

Target: ARHGEF5 (rho Guanine Nucleotide Exchange Factor (GEF) 5 (ARHGEF5))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ARHGEF5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)

Aufreinigung: Immunogen affinity purified

Reinheit: ≥95 % as determined by SDS-PAGE

Immunogen: Rho guanine nucleotide exchange factor(GEF) 5

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:2000, IP: 1:200-1:1000, IHC: 1:20-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Haltbarkeit: 12 months

Details zu ARHGEF5

Target: ARHGEF5 (rho Guanine Nucleotide Exchange Factor (GEF) 5 (ARHGEF5))

Andere Bezeichnung: ARHGEF5 (ARHGEF5 Produkte)

Synonyme: ARHGEF5 antikoerper, GEF5 antikoerper, P60 antikoerper, TIM antikoerper, TIM1 antikoerper, 2210412D05Rik antikoerper, AA717842 antikoerper, AW495314 antikoerper, Tim1 antikoerper, Rho guanine nucleotide exchange factor 5 antikoerper, rho guanine nucleotide exchange factor 5 antikoerper, Rho guanine nucleotide exchange factor (GEF) 5 antikoerper, ARHGEF5 antikoerper, LOC100414419 antikoerper, Arhgef5 antikoerper

Hintergrund: Synonyms:TIM Background:Guanine nucleotide exchange factor which activates Rho GTPases(PubMed:15601624). Strongly activates RHOA(PubMed:15601624). Also strongly activates RHOB, weakly activates RHOC and RHOG and shows no effect on RHOD, RHOV, RHOQ or RAC1(By similarity). Involved in regulation of cell shape and actin cytoskeletal organization(PubMed:15601624). Plays a role in actin organization by generating a loss of actin stress fibers and the formation of membrane ruffles and filopodia(PubMed:14662653). Required for SRC-induced podosome formation(By similarity). Involved in positive regulation of immature dendritic cell migration(By similarity).

Molekulargewicht: 60 kDa

Gen-ID: 7984

UniProt: Q12774