REST Antikörper
Kurzübersicht für REST Antikörper (ABIN7118333)
Target
Alle REST Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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    - 
                                            Aufreinigung
- Immunogen affinity purified
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                                            Reinheit
- ≥95 % as determined by SDS-PAGE
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                                            Immunogen
- RE1-silencing transcription factor
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                                            Isotyp
- IgG
 
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    - 
                                            Applikationshinweise
- WB: 1:500-1:1000, IP: 1:500-1:2000
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                                            Beschränkungen
- Nur für Forschungszwecke einsetzbar
 
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    - 
                                            Format
- Liquid
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                                            Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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                                            Konservierungsmittel
- Sodium azide
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                                            Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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                                            Lagerung
- -20 °C
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                                            Informationen zur Lagerung
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
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                                            Haltbarkeit
- 12 months
 
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    - REST (RE1-Silencing Transcription Factor (REST))
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                                            Andere Bezeichnung
- REST
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                                            Hintergrund
- Synonyms:NRSF, REST, X2 box repressor, XBR Background:Transcriptional repressor which binds neuron-restrictive silencer element(NRSE) and represses neuronal gene transcription in non-neuronal cells. Restricts the expression of neuronal genes by associating with two distinct corepressors, mSin3 and CoREST, which in turn recruit histone deacetylase to the promoters of REST-regulated genes. Mediates repression by recruiting the BHC complex at RE1/NRSE sites which acts by deacetylating and demethylating specific sites on histones, thereby acting as a chromatin modifier. Transcriptional repression by REST-CDYL via the recruitment of histone methyltransferase EHMT2 may be important in transformation suppression.
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                                            Molekulargewicht
- 122 kDa, 200kd
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                                            Gen-ID
- 5978
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                                            UniProt
- Q13127
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                                            Pathways
- Negative Regulation of Hormone Secretion, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Chromatin Binding, Positive Regulation of Endopeptidase Activity
 Target
- 
                    
 
                                     
                                     
                                    