RASGRP2 Antikörper
Kurzübersicht für RASGRP2 Antikörper (ABIN7118303)
Target
Alle RASGRP2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Verwendungszweck
- RASGRP2 antibody
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Aufreinigung
- Immunogen affinity purified
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Reinheit
- ≥95 % as determined by SDS-PAGE
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Immunogen
- RAS guanyl releasing protein 2(calcium and DAG-regulated)
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Isotyp
- IgG
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Applikationshinweise
- WB: 1:500-1:2000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze / thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- -20°C for 12 months
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Haltbarkeit
- 12 months
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- RASGRP2 (RAS Guanyl Releasing Protein 2 (Calcium and DAG-Regulated) (RASGRP2))
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Andere Bezeichnung
- RASGRP2
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Hintergrund
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Synonyms: RAS guanyl-releasing protein 2|Calcium and DAG-regulated guanine nucleotide exchange factor I (CalDAG-GEFI)|Cdc25-like protein (hCDC25L)|F25B3.3 kinase-like protein|RASGRP2|CDC25L|MCG7
Background: Functions as a calcium-and DAG-regulated nucleotide exchange factor specifically activating Rap through the exchange of bound GDP for GTP. May also activates other GTPases such as RRAS, RRAS2, NRAS, KRAS but not HRAS. Functions in aggregation of platelets and adhesion of T-lymphocytes and neutrophils probably through inside-out integrin activation. May function in the muscarinic acetylcholine receptor M1/CHRM1 signaling pathway.
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Molekulargewicht
- 48 kDa
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Gen-ID
- 10235
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UniProt
- Q7LDG7
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Pathways
- T-Zell Rezeptor Signalweg
Target
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