RAB43 Antikörper

Produktnummer ABIN7118226

Dieses Anti-RAB43-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von RAB43 in WB und ELISA. Geeignet für Human, Maus und Ratte.

Kurzübersicht für RAB43 Antikörper (ABIN7118226)

Target: RAB43 (RAB43, Member RAS Oncogene Family (RAB43))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RAB43 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-RAB43 Antikörper

Verwendungszweck: RAB43 antibody

Aufreinigung: Immunogen affinity purified

Reinheit: ≥95 % as determined by SDS-PAGE

Immunogen: RAB43, member RAS oncogene family

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C for 12 months

Haltbarkeit: 12 months

Details zu RAB43

Target: RAB43 (RAB43, Member RAS Oncogene Family (RAB43))

Andere Bezeichnung: RAB43

Hintergrund:

Synonyms: Ras-related protein Rab-43|Ras-related protein Rab-41|RAB43|RAB41

Background: The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. The low intrinsic GTPase activity of RAB43 is activated by USP6NL. Involved in retrograde transport from the endocytic pathway to the Golgi apparatus. Involved in the transport of Shiga toxin from early and recycling endosomes to the trans-Golgi network. Required for the structural integrity of the Golgi complex. Plays a role in the maturation of phagosomes that engulf pathogens, such as S.aureus and M.tuberculosis.

Molekulargewicht: 23 kDa

Gen-ID: 339122

UniProt: Q86YS6