RAB43 Antikörper (Internal Region)

Produktnummer ABIN6264583

Produktdetails anti-RAB43 Antikörper

Target: RAB43 (RAB43, Member RAS Oncogene Family (RAB43))

Bindungsspezifität: Internal Region

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RAB43 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Spezifität: RAB43 Antibody detects endogenous levels of total RAB43.

Homologie: Pig,Horse

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human RAB43, corresponding to a region within the internal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:1000-3000, IHC 1:200, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu RAB43

Target: RAB43 (RAB43, Member RAS Oncogene Family (RAB43))

Andere Bezeichnung: RAB43 (RAB43 Produkte)

Synonyme: rab43 antikoerper, fi21h07 antikoerper, wu:fi21h07 antikoerper, zgc:136785 antikoerper, RAB11B antikoerper, RAB41 antikoerper, 1810048P08Rik antikoerper, 2500004H21Rik antikoerper, AW490415 antikoerper, RAB43, member RAS oncogene family antikoerper, ISY1 splicing factor homolog antikoerper, RAB43 antikoerper, rab43 antikoerper, isy1 antikoerper, Rab43 antikoerper

Hintergrund:

Description: The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. The low intrinsic GTPase activity of RAB43 is activated by USP6NL. Involved in retrograde transport from the endocytic pathway to the Golgi apparatus. Involved in the transport of Shiga toxin from early and recycling endosomes to the trans-Golgi network. Required for the structural integrity of the Golgi complex. Plays a role in the maturation of phagosomes that engulf pathogens, such as S.aureus and M.tuberculosis.

Gene: RAB43

Molekulargewicht: 23 kDa

Gen-ID: 339122

UniProt: Q86YS6