RAB35 Antikörper

Produktnummer ABIN7118213

Der Kaninchen Polyklonal Anti-RAB35-Antikörper wurde für ELISA, WB, IHC, IF und IP validiert. Er ist geeignet, RAB35 in Proben von Human, Ratte und Maus zu detektieren.

Kurzübersicht für RAB35 Antikörper (ABIN7118213)

Target: RAB35 (RAB35, Member RAS Oncogene Family (RAB35))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RAB35 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)

Produktdetails anti-RAB35 Antikörper

Verwendungszweck: RAB35 antibody

Aufreinigung: Immunogen affinity purified

Reinheit: ≥95 % as determined by SDS-PAGE

Immunogen: RAB35, member RAS oncogene family

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:2000, IP: 1:200-1:1000, IHC: 1:20-1:200, IF: 1:20-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C for 12 months

Haltbarkeit: 12 months

Details zu RAB35

Target: RAB35 (RAB35, Member RAS Oncogene Family (RAB35))

Andere Bezeichnung: RAB35

Hintergrund:

Synonyms: Ras-related protein Rab-35|GTP-binding protein RAY|Ras-related protein Rab-1C|RAB35|RAB1C|RAY

Background: The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. That Rab is involved in the process of endocytosis and is an essential rate-limiting regulator of the fast recycling pathway back to the plasma membrane. During cytokinesis, required for the postfurrowing terminal steps, namely for intercellular bridge stability and abscission, possibly by controlling phosphatidylinositol 4,5-bis phosphate(PIP2) and SEPT2 localization at the intercellular bridge. May indirectly regulate neurite outgrowth.

Molekulargewicht: 25 kDa

Gen-ID: 11021

UniProt: Q15286