PSMD7 Antikörper

Produktnummer ABIN7117896

Dieses Anti-PSMD7-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von PSMD7 in WB, ELISA, IHC und IF. Geeignet für Human und Maus.

Kurzübersicht für PSMD7 Antikörper (ABIN7117896)

Target: PSMD7 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 7 (PSMD7))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PSMD7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-PSMD7 Antikörper

Verwendungszweck: PSMD7 antibody

Aufreinigung: Immunogen affinity purified

Reinheit: ≥95 % as determined by SDS-PAGE

Immunogen: proteasome (prosome, macropain) 26S subunit, non-ATPase, 7

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200, IF: 1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C for 12 months

Haltbarkeit: 12 months

Details zu PSMD7

Target: PSMD7 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 7 (PSMD7))

Andere Bezeichnung: PSMD7

Hintergrund:

Synonyms: 26S proteasome non-ATPase regulatory subunit 7|26S proteasome regulatory subunit RPN8|26S proteasome regulatory subunit S12|Mov34 protein homolog|Proteasome subunit p40|PSMD7|MOV34L

Background: The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator. A pseudogene has been identified on chromosome 17.

Molekulargewicht: 38 kDa

Gen-ID: 5713

UniProt: P51665

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA, Ubiquitin Proteasome Pathway