Dieses Anti-PDCD4-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von PDCD4 in WB, ELISA, IHC, IP und FACS. Geeignet für Human, Maus und Ratte.
PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C
Informationen zur Lagerung
-20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Haltbarkeit
12 months
Target
PDCD4
(Programmed Cell Death 4 (PDCD4))
Andere Bezeichnung
PDCD4
Hintergrund
Synonyms:H731, Nuclear antigen H731 like, PDCD4, Protein 197/15a Background:Inhibits translation initiation and cap-dependent translation. May excert its function by hindering the interaction between EIF4A1 and EIF4G. Inhibits the helicase activity of EIF4A. Modulates the activation of JUN kinase. Down-regulates the expression of MAP4K1, thus inhibiting events important in driving invasion, namely, MAPK85 activation and consequent JUN-dependent transcription. May play a role in apoptosis. Tumor suppressor. Inhibits tumor promoter-induced neoplastic transformation. Binds RNA(By similarity).