ProGRP Antikörper

Produktnummer ABIN7117775

Der Kaninchen Polyklonal Anti-ProGRP-Antikörper wurde für WB, IHC und ELISA validiert. Er ist geeignet, ProGRP in Proben von Human zu detektieren.

Kurzübersicht für ProGRP Antikörper (ABIN7117775)

Target: ProGRP (Pro-Gastrin-Releasing Peptide (ProGRP))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ProGRP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Produktdetails anti-ProGRP Antikörper

Aufreinigung: Immunogen affinity purified

Reinheit: ≥95 % as determined by SDS-PAGE

Immunogen: gastrin-releasing peptide

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:2000, IHC: 1:20-1:200, IF: 1:20-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Haltbarkeit: 12 months

Details zu ProGRP

Target: ProGRP (Pro-Gastrin-Releasing Peptide (ProGRP))

Andere Bezeichnung: ProGRP

Hintergrund: Synonyms:BN, gastrin releasing peptide, GRP, GRP 10, preproGRP, proGRP Background:Gastrin-releasing peptide, also known as GRP, is normally formed by mucosal cells in the gastric antrum and by the D cells of the pancreatic islets, and its main function is to stimulate secretion of HCl by the gastric mucosa. HCl, in turn, inhibits gastrin formation. Its 148-amino acid preproprotein, following cleavage of a signal peptide, is further processed to produce either the 27-amino acid gastrin-releasing peptide or the 10-amino acid neuromedin C. These smaller peptides regulate numerous functions of the gastrointestinal and central nervous systems, including release of gastrointestinal hormones, smooth muscle cell contraction, and epithelial cell proliferation.These peptides are also likely to play a role in human cancers of the lung, colon, stomach, pancreas, breast, and prostate.

Molekulargewicht: 16kd,32kd

Gen-ID: 2922

UniProt: P07492

Pathways: Peptide Hormone Metabolism, Hormone Activity