Der Kaninchen Polyklonal Anti-PCM1-Antikörper wurde für WB, IHC und ELISA validiert. Er ist geeignet, PCM1 in Proben von Human und Maus zu detektieren.
PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3 ,
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C
Informationen zur Lagerung
-20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Haltbarkeit
12 months
Target
PCM1
(Pericentriolar Material 1 (PCM1))
Andere Bezeichnung
PCM1
Hintergrund
Synonyms: Background:The protein encoded by this gene is a component of centriolar satellites, which are electron dense granules scattered around centrosomes. Inhibition studies show that this protein is essential for the correct localization of several centrosomal proteins, and for anchoring microtubules to the centrosome. Chromosomal aberrations involving this gene are associated with papillary thyroid carcinomas and a variety of hematological malignancies, including atypical chronic myeloid leukemia and T-cell lymphoma. Multiple transcript variants encoding different isoforms have been found for this gene.