P-Glycoprotein Antikörper
Kurzübersicht für P-Glycoprotein Antikörper (ABIN7117181)
Target
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
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Aufreinigung
- Immunogen affinity purified
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Reinheit
- ≥95 % as determined by SDS-PAGE
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Immunogen
- ABCB1
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Isotyp
- IgG
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Applikationshinweise
- WB: 1:200-1:1000, IP: 1:200-1:1000, IHC: 1:50-1:500
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
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Haltbarkeit
- 12 months
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- P-Glycoprotein
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Andere Bezeichnung
- P Glycoprotein
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Hintergrund
- Synonyms:ABCB1, CD243, GP170, MDR1, Multidrug resistance protein 1, P glycoprotein 1 Background:ABCB1(also known as P-gp/ P-glycoprotein, MDR1/multidrug-resistance 1) is a plasma membrane protein first discovered in multidrug resistant tumor cells. ABCB1 can extrude a large number of medically relevant compounds from cells and causes drug resistance. ABCB1 is expressed in a variety of human cancers as well as normal tissues including brain, and placenta. Overexpression of ABCB1 correlates with a negative prognosis in several types of cancer.
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Molekulargewicht
- 142 kDa
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Gen-ID
- 5243
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UniProt
- P08183
Target
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