NCOA3
Reaktivität: Human
ELISA
Wirt: Maus
Monoclonal
2C11B12
unconjugated
Applikationshinweise
WB: 1:500-1:2000, IHC: 1:20-1:200, IF: 1:20-1:200
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Buffer
PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C
Informationen zur Lagerung
-20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Haltbarkeit
12 months
Target
NCOA3
(Nuclear Receptor Coactivator 3 (NCOA3))
Andere Bezeichnung
NCOA3
Hintergrund
Synonyms:AIB1, BHLHE42, RAC3, TRAM1 Background:Nuclear receptor coactivator that directly binds nuclear receptors and stimulates the transcriptional activities in a hormone-dependent fashion. Plays a central role in creating a multisubunit coactivator complex, which probably acts via remodeling of chromatin. Involved in the coactivation of different nuclear receptors, such as for steroids(GR and ER), retinoids(RARs and RXRs), thyroid hormone(TRs), vitamin D3(VDR) and prostanoids(PPARs). Displays histone acetyltransferase activity. Also involved in the coactivation of the NF-kappa-B pathway via its interaction with the NFKB1 subunit.