NFIL3 Antikörper

Produktnummer ABIN7116970

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch NFIL3 in WB, ELISA und IP. Er zeigt eine Reaktivität gegenüber Human, Maus und Ratte.

Kurzübersicht für NFIL3 Antikörper (ABIN7116970)

Target: NFIL3 (Nuclear Factor, Interleukin 3 Regulated (NFIL3))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NFIL3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunoprecipitation (IP)

Produktdetails anti-NFIL3 Antikörper

Verwendungszweck: NFIL3 antibody

Aufreinigung: Immunogen affinity purified

Reinheit: ≥95 % as determined by SDS-PAGE

Immunogen: nuclear factor, interleukin 3 regulated

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:2000, IP: 1:200-1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C for 12 months

Haltbarkeit: 12 months

Details zu NFIL3

Target: NFIL3 (Nuclear Factor, Interleukin 3 Regulated (NFIL3))

Andere Bezeichnung: NFIL3

Hintergrund:

Synonyms: Nuclear factor interleukin-3-regulated protein|E4 promoter-binding protein 4|Interleukin-3 promoter transcriptional activator|Interleukin-3-binding protein 1|Transcriptional activator NF-IL3A|NFIL3|E4BP4|IL3BP1

Background: Acts as a transcriptional regulator that recognizes and binds to the sequence 5'-[GA]TTA[CT]GTAA[CT]-3', a sequence present in many cellular and viral promoters. Represses transcription from promoters with activating transcription factor(ATF) sites. Represses promoter activity in osteoblasts(By similarity). Represses transcriptional activity of PER1(By similarity). Represses transcriptional activity of PER2 via the B-site on the promoter(By similarity). Activates transcription from the interleukin-3 promoter in T-cells. Competes for the same consensus-binding site with PAR DNA-binding factors(DBP, HLF and TEF)(By similarity). Component of the circadian clock that acts as a negative regulator for the circadian expression of PER2 oscillation in the cell-autonomous core clock(By similarity). Protects pro-B cells from programmed cell death(By similarity).

Molekulargewicht: 55-60 kDa

Gen-ID: 4783

UniProt: Q16649