NLRP2 Antikörper
Kurzübersicht für NLRP2 Antikörper (ABIN7116907)
Target
Alle NLRP2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Verwendungszweck
- NLRP2 antibody
-
Aufreinigung
- Immunogen affinity purified
-
Reinheit
- ≥95 % as determined by SDS-PAGE
-
Immunogen
- NLR family, pyrin domain containing 2
-
Isotyp
- IgG
-
-
anti-NLR Family, Pyrin Domain Containing 2 (NLRP2) (AA 1-1062) antibody
NLRP2 Reaktivität: Human WB, IF, IP Wirt: Kaninchen Polyclonal unconjugated
anti-NLR Family, Pyrin Domain Containing 2 (NLRP2) (AA 1-220) antibodyNLRP2 Reaktivität: Human WB, IF Wirt: Kaninchen Polyclonal unconjugated
anti-NLR Family, Pyrin Domain Containing 2 (NLRP2) (AA 1-220) antibodyNLRP2 Reaktivität: Human WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-NLR Family, Pyrin Domain Containing 2 (NLRP2) (C-Term) antibodyNLRP2 Reaktivität: Human, Maus, Ratte WB, IHC, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-NLR Family, Pyrin Domain Containing 2 (NLRP2) (C-Term) antibodyVerified NLRP2 Reaktivität: Human WB, ELISA Wirt: Ziege Polyclonal unconjugated
anti-NLR Family, Pyrin Domain Containing 2 (NLRP2) (AA 1-846) antibodyNLRP2 Reaktivität: Human ELISA Wirt: Maus Monoclonal 1B10 unconjugated
anti-NLR Family, Pyrin Domain Containing 2 (NLRP2) (AA 1-1062) antibodyNLRP2 Reaktivität: Human WB Wirt: Maus Polyclonal unconjugated
anti-NLR Family, Pyrin Domain Containing 2 (NLRP2) (AA 620-732) antibodyNLRP2 Reaktivität: Human, Maus, Ratte, Huhn, Hund WB, IF Wirt: Maus Monoclonal 34-NBS1 unconjugated
anti-NLR Family, Pyrin Domain Containing 2 (NLRP2) antibodyNLRP2 Reaktivität: Human FACS, Func Wirt: Maus Monoclonal 8F10B51 unconjugated
anti-NLR Family, Pyrin Domain Containing 2 (NLRP2) (AA 150-200) antibodyNLRP2 Reaktivität: Human, Maus WB, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
-
-
Applikationshinweise
- WB: 1:500-1:2000, IHC: 1:20-1:200
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Handhabung
- Avoid repeated freeze / thaw cycles.
-
Lagerung
- -20 °C
-
Informationen zur Lagerung
- -20°C for 12 months
-
Haltbarkeit
- 12 months
-
-
- NLRP2 (NLR Family, Pyrin Domain Containing 2 (NLRP2))
-
Andere Bezeichnung
- NLRP2
-
Hintergrund
-
Synonyms: NACHT, LRR and PYD domains-containing protein 2|Nucleotide-binding site protein 1|PYRIN domain and NACHT domain-containing protein 1|PYRIN-containing APAF1-like protein 2|NLRP2|NALP2|NBS1|PAN1|PYPAF2
Background: Suppresses TNF-and CD40-induced NFKB1 activity at the level of the IKK complex, by inhibiting NFKBIA degradation induced by TNF. When associated with PYCARD, activates CASP1, leading to the secretion of mature proinflammatory cytokine IL1B. May be a component of the inflammasome, a protein complex which also includes PYCARD, CARD8 and CASP1 and whose function would be the activation of proinflammatory caspases.
-
Molekulargewicht
- 105-110 kDa
-
Gen-ID
- 55655
-
UniProt
- Q9NX02
-
Pathways
- Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity, Inflammasome
Target
-
