MIA3 Antikörper

Produktnummer ABIN7116180

Dieses Anti-MIA3-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von MIA3 in ELISA, WB und IP. Geeignet für Human, Maus und Ratte.

Kurzübersicht für MIA3 Antikörper (ABIN7116180)

Target: MIA3 (Melanoma Inhibitory Activity Family, Member 3 (MIA3))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MIA3 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunoprecipitation (IP)

Produktdetails anti-MIA3 Antikörper

Verwendungszweck: MIA3 antibody

Aufreinigung: Immunogen affinity purified

Reinheit: ≥95 % as determined by SDS-PAGE

Immunogen: melanoma inhibitory activity family, member 3

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:2000, IP: 1:200-1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C for 12 months

Haltbarkeit: 12 months

Details zu MIA3

Target: MIA3 (Melanoma Inhibitory Activity Family, Member 3 (MIA3))

Andere Bezeichnung: MIA3

Hintergrund:

Synonyms: Transport and Golgi organization protein 1 homolog (TANGO1)|C219-reactive peptide|D320|Melanoma inhibitory activity protein 3|MIA3|KIAA0268|TANGO

Background: Plays a role in the transport of cargos that are too large to fit into COPII-coated vesicles and require specific mechanisms to be incorporated into membrane-bound carriers and exported from the endoplasmic reticulum. This protein is required for collagen VII(COL7A1) secretion by loading COL7A1 into transport carriers. It may participate in cargo loading of COL7A1 at endoplasmic reticulum exit sites by binding to COPII coat subunits Sec23/24 and guiding SH3-bound COL7A1 into a growing carrier. Does not play a role in global protein secretion and is apparently specific to COL7A1 cargo loading. However, it may participate in secretion of other proteins in cells that do not secrete COL7A1. It is also specifically required for the secretion of lipoproteins by participating in their export from the endoplasmic reticulum(PubMed:27138255).

Molekulargewicht: 250-300 kDa

Gen-ID: 375056

UniProt: Q5JRA6