MAGED1 Antikörper

Produktnummer ABIN7116167

Produktdetails anti-MAGED1 Antikörper

Target: MAGED1 (Melanoma Antigen Family D, 1 (MAGED1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MAGED1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Aufreinigung: Immunogen affinity purified

Reinheit: ≥95 % as determined by SDS-PAGE

Immunogen: melanoma antigen family D, 1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:2000, IHC: 1:20-1:200, IF: 1:20-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Haltbarkeit: 12 months

Details zu MAGED1

Target: MAGED1 (Melanoma Antigen Family D, 1 (MAGED1))

Andere Bezeichnung: MAGED1 (MAGED1 Produkte)

Synonyme: MAGED1 antikoerper, DLXIN-1 antikoerper, NRAGE antikoerper, 2810433C11Rik antikoerper, 5430405L04Rik antikoerper, DXBwg1492e antikoerper, Dlixin antikoerper, Dlxin-1 antikoerper, Dlxin1 antikoerper, MAGE-D1 antikoerper, mFLJ00163 antikoerper, Nrage antikoerper, MAGE family member D1 antikoerper, melanoma antigen family D, 1 antikoerper, melanoma antigen, family D, 1 antikoerper, MAGED1 antikoerper, Maged1 antikoerper

Hintergrund: Synonyms:NRAGE Background:Involved in the apoptotic response after nerve growth factor(NGF) binding in neuronal cells. Inhibits cell cycle progression, and facilitates NGFR-mediated apoptosis. May act as a regulator of the function of DLX family members. May enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzyme(E2) at the E3:substrate complex. Plays a role in the circadian rythm regulation. May act as RORA co-regulator, modulating the expression of core clock genes such as ARNTL/BMAL1 and NFIL3, induced, or NR1D1, repressed.

Molekulargewicht: 100 kDa

Gen-ID: 9500

UniProt: Q9Y5V3

Pathways: Neurotrophin Signalübertragung