Der Kaninchen Polyklonal Anti-MAGED1-Antikörper wurde für WB, IHC, ELISA und IF validiert. Er ist geeignet, MAGED1 in Proben von Human, Maus und Ratte zu detektieren.
MAGED1
Reaktivität: Human
WB, ELISA
Wirt: Maus
Monoclonal
1G11
unconjugated
Applikationshinweise
WB: 1:500-1:2000, IHC: 1:20-1:200, IF: 1:20-1:200
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Buffer
PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C
Informationen zur Lagerung
-20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Haltbarkeit
12 months
Target
MAGED1
(Melanoma Antigen Family D, 1 (MAGED1))
Andere Bezeichnung
MAGED1
Hintergrund
Synonyms:NRAGE Background:Involved in the apoptotic response after nerve growth factor(NGF) binding in neuronal cells. Inhibits cell cycle progression, and facilitates NGFR-mediated apoptosis. May act as a regulator of the function of DLX family members. May enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzyme(E2) at the E3:substrate complex. Plays a role in the circadian rythm regulation. May act as RORA co-regulator, modulating the expression of core clock genes such as ARNTL/BMAL1 and NFIL3, induced, or NR1D1, repressed.