MAML1 Antikörper
Kurzübersicht für MAML1 Antikörper (ABIN7116076)
Target
Alle MAML1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Verwendungszweck
- MAML1 antibody
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Aufreinigung
- Immunogen affinity purified
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Reinheit
- ≥95 % as determined by SDS-PAGE
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Immunogen
- mastermind-like 1(Drosophila)
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Isotyp
- IgG
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anti-Mastermind-Like 1 (MAML1) (N-Term) antibody
MAML1 Reaktivität: Human, Maus WB, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Mastermind-Like 1 (MAML1) (AA 1-45) antibodyMAML1 Reaktivität: Human ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Mastermind-Like 1 (MAML1) (AA 198-225) antibodyMAML1 Reaktivität: Human WB, FACS Wirt: Kaninchen Polyclonal RB18757 unconjugated
anti-Mastermind-Like 1 (MAML1) (N-Term) antibodyVerified MAML1 Reaktivität: Human ELISA, WB, IHC Wirt: Ziege Polyclonal unconjugated
anti-Mastermind-Like 1 (MAML1) (AA 655-754) antibodyMAML1 Reaktivität: Human ELISA, WB Wirt: Maus Polyclonal unconjugated
anti-Mastermind-Like 1 (MAML1) (AA 205-234), (Middle Region) antibodyMAML1 Reaktivität: Human WB, FACS, EIA Wirt: Kaninchen Polyclonal unconjugated
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Applikationshinweise
- WB: 1:500-1:2000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze / thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- -20°C for 12 months
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Haltbarkeit
- 12 months
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- MAML1 (Mastermind-Like 1 (MAML1))
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Andere Bezeichnung
- MAML1
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Hintergrund
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Synonyms: Mastermind-like protein 1 (Mam-1)|MAML1|KIAA0200
Background: Acts as a transcriptional coactivator for NOTCH proteins. Has been shown to amplify NOTCH-induced transcription of HES1. Enhances phosphorylation and proteolytic turnover of the NOTCH intracellular domain in the nucleus through interaction with CDK8. Binds to CREBBP/CBP which promotes nucleosome acetylation at NOTCH enhancers and activates transcription. Induces phosphorylation and localization of CREBBP to nuclear foci. Plays a role in hematopoietic development by regulating NOTCH-mediated lymphoid cell fate decisions.
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Molekulargewicht
- 108-120 kDa
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Gen-ID
- 9794
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UniProt
- Q92585
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Pathways
- Notch Signalweg, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
Target
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