KNG1 Antikörper
Kurzübersicht für KNG1 Antikörper (ABIN7115720)
Target
Alle KNG1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Verwendungszweck
- KNG1 antibody
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Aufreinigung
- Immunogen affinity purified
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Reinheit
- ≥95 % as determined by SDS-PAGE
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Immunogen
- Kininogen-1
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Isotyp
- IgG
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Applikationshinweise
- WB: 1:500-1:2000, IF: 1:50-1:200
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze / thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- -20°C for 12 months
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Haltbarkeit
- 12 months
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- KNG1 (Kininogen 1 (KNG1))
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Andere Bezeichnung
- KNG1
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Hintergrund
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Synonyms: Kininogen-1|Alpha-2-thiol proteinase inhibitor|Fitzgerald factor|High molecular weight kininogen (HMWK)|Williams-Fitzgerald-Flaujeac factor|Kininogen-1 heavy chain|T-kinin Alternative names: Ile-Ser-Bradykinin|Bradykinin Alternative names: Kallidin I|Lysyl-bradykinin Alternative names: Kallidin II|Kininogen-1 light chain|Low molecular weight growth-promoting factor|KNG1|BDK|KNG
Background: This gene uses alternative splicing to generate two different proteins- high molecular weight kininogen (HMWK) and low molecular weight kininogen (LMWK). HMWK is essential for blood coagulation and assembly of the kallikrein-kinin system. Also, bradykinin, a peptide causing numerous physiological effects, is released from HMWK. Bradykinin also functions as an antimicrobial peptide with antibacterial and antifungal activity. In contrast to HMWK, LMWK is not involved in blood coagulation. Three transcript variants encoding different isoforms have been found for this gene.
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Molekulargewicht
- 68 kDa
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Gen-ID
- 3827
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UniProt
- P01042
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Pathways
- ACE Inhibitor Pathway, Glycosaminoglycan Metabolic Process
Target
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