IL23A Antikörper (AA 20-189)
Kurzübersicht für IL23A Antikörper (AA 20-189) (ABIN7115450)
Target
Alle IL23A Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 20-189
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Verwendungszweck
- IL23A antibody
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Aufreinigung
- Protein A+G purification
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Reinheit
- ≥95 % as determined by SDS-PAGE
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Immunogen
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Immunogen sequence: 20-189aa
Immunogen: interleukin 23, alpha subunit p19
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Isotyp
- IgG1
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Applikationshinweise
- WB: 1:500-1:2000, IHC: 1:20-1:200
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze / thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- -20°C for 12 months
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Haltbarkeit
- 12 months
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- IL23A (Interleukin 23, alpha subunit p19 (IL23A))
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Andere Bezeichnung
- IL23A
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Hintergrund
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Synonyms: Interleukin-23 subunit alpha (IL-23 subunit alpha, IL-23-A)|Interleukin-23 subunit p19 (IL-23p19)|IL23A|SGRF
Background: Associates with IL12B to form the IL-23 interleukin, a heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T-cells and promotes production of proinflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis.
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Molekulargewicht
- 21 kDa
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Gen-ID
- 51561
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UniProt
- Q9NPF7
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Pathways
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation
Target
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