IL23A Antikörper

Produktnummer ABIN1169135

Der Ratte Monoklonal anti-IL23A Antikörper wird verwendet zum Nachweis von IL23A in Proben von Human. Er wurde validiert für WB und ELISA.

Kurzübersicht für IL23A Antikörper (ABIN1169135)

Target: IL23A (Interleukin 23, alpha subunit p19 (IL23A))

Reaktivität: Human

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser IL23A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Klon: I 178G

Produktdetails anti-IL23A Antikörper

Verwendungszweck: anti-IL-23p19 (human), mAb (I 178G)

Spezifität: Recognizes human IL-23p19.

Produktmerkmale: Monoclonal Antibody. Recognizes human IL-23p19. Isotype: Rat IgG2akappa. Clone: I 178G. Applications: ELISA, WB. Liquid. 0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives. IL-23p19 associates with IL-12b to form the IL-23 interleukin, an heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 binds to an heterodimeric receptor complex composed of IL-12RB1 and IL-23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T-cells and promotes production of proinflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis.

Sterilität: 0.2 μm filtered

Immunogen: Recombinant human IL-23p19.

Isotyp: IgG2a kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 0.2μm-filtered solution in PBS, pH 7.4.

Konservierungsmittel: Without preservative

Handhabung: After opening, prepare aliquots and store at -20 °C.Avoid freeze/thaw cycles.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung:

+4°C

-20°C

Stable for at least 1 year after receipt when stored at -20°C.

Haltbarkeit: 12 months

Details zu IL23A

Target: IL23A (Interleukin 23, alpha subunit p19 (IL23A))

Andere Bezeichnung: IL-23p19

Hintergrund:

Alternate Names/Synonyms: Interleukin-23 Subunit p19, Interleukin-23 Subunit alpha, IL-23-A

Product Description: IL-23p19 associates with IL-12b to form the IL-23 interleukin, an heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 binds to an heterodimeric receptor complex composed of IL-12RB1 and IL-23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T-cells and promotes production of proinflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis.

UniProt: Q9NPF7

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation