HOPX Antikörper
Kurzübersicht für HOPX Antikörper (ABIN7115108)
Target
Alle HOPX Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Verwendungszweck
- HOPX antibody
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Aufreinigung
- Immunogen affinity purified
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Reinheit
- ≥95 % as determined by SDS-PAGE
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Immunogen
- HOP homeobox
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Isotyp
- IgG
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Applikationshinweise
- WB: 1:500-1:2000, IF: 1:50-1:200
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze / thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- -20°C for 12 months
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Haltbarkeit
- 12 months
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- HOPX (HOP Homeobox (HOPX))
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Andere Bezeichnung
- HOPX
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Hintergrund
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Synonyms: Homeodomain-only protein|Lung cancer-associated Y protein|Not expressed in choriocarcinoma protein 1|Odd homeobox protein 1|HOPX|HOD|HOP|LAGY|NECC1|OB1
Background: Atypical homeodomain protein which does not bind DNA and is required to modulate cardiac growth and development. Acts via its interaction with SRF, thereby modulating the expression of SRF-dependent cardiac-specific genes and cardiac development. Prevents SRF-dependent transcription either by inhibiting SRF binding to DNA or by recruiting histone deacetylase(HDAC) proteins that prevent transcription by SRF. Overexpression causes cardiac hypertrophy(By similarity). May act as a tumor suppressor.
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Molekulargewicht
- 8-12 kDa
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Gen-ID
- 84525
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UniProt
- Q9BPY8
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Pathways
- Regulation of Muscle Cell Differentiation
Target
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