HOPX Antikörper (C-Term)

Produktnummer ABIN6257752

Produktdetails anti-HOPX Antikörper

Target: HOPX (HOP Homeobox (HOPX))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HOPX Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Spezifität: HOP Antibody detects endogenous levels of total HOP.

Homologie: Pig,Bovine,Horse,Rabbit,Dog,Chicken

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human HOP, corresponding to a region within C-terminal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Haltbarkeit: 12 months

Details zu HOPX

Target: HOPX (HOP Homeobox (HOPX))

Andere Bezeichnung: HOPX (HOPX Produkte)

Synonyme: CAMEO antikoerper, HOD antikoerper, HOP antikoerper, LAGY antikoerper, NECC1 antikoerper, OB1 antikoerper, SMAP31 antikoerper, TOTO antikoerper, 1110018K11Rik antikoerper, 1200015P04Rik antikoerper, 2300002F06Rik antikoerper, AI848177 antikoerper, AW490897 antikoerper, Cameo antikoerper, Hdop antikoerper, Hod antikoerper, Hop antikoerper, Ob1 antikoerper, Obl antikoerper, Toto antikoerper, GIIg15b antikoerper, HOPX antikoerper, hod antikoerper, hop antikoerper, ob1 antikoerper, lagy antikoerper, toto antikoerper, cameo antikoerper, necc1 antikoerper, smap31 antikoerper, MGC147344 antikoerper, HOP homeobox antikoerper, HOPX antikoerper, Hopx antikoerper, hopx antikoerper

Hintergrund:

Description: Atypical homeodomain protein which does not bind DNA and is required to modulate cardiac growth and development. Acts via its interaction with SRF, thereby modulating the expression of SRF-dependent cardiac-specific genes and cardiac development. Prevents SRF-dependent transcription either by inhibiting SRF binding to DNA or by recruiting histone deacetylase (HDAC) proteins that prevent transcription by SRF. Overexpression causes cardiac hypertrophy (By similarity). May act as a tumor suppressor. Acts as a co-chaperone for HSPA1A and HSPA1B chaperone proteins and assists in chaperone-mediated protein refolding (PubMed:27708256).

Gene: HOPX

Molekulargewicht: 8 kDa

Gen-ID: 84525

UniProt: Q9BPY8

Pathways: Regulation of Muscle Cell Differentiation