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HOMER1 Antikörper

HOMER1 Reaktivität: Human, Maus WB, ELISA, IHC, FACS, IP Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7115100
  • Target Alle HOMER1 Antikörper anzeigen
    HOMER1 (Homer Homolog 1 (HOMER1))
    Reaktivität
    • 36
    • 18
    • 10
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Maus
    Wirt
    • 33
    • 7
    • 1
    • 1
    Kaninchen
    Klonalität
    • 34
    • 6
    • 1
    Polyklonal
    Konjugat
    • 27
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser HOMER1 Antikörper ist unkonjugiert
    Applikation
    • 30
    • 14
    • 13
    • 4
    • 4
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunoprecipitation (IP)
    Aufreinigung
    Immunogen affinity purified
    Reinheit
    ≥95 % as determined by SDS-PAGE
    Immunogen
    homer homolog 1(Drosophila)
    Isotyp
    IgG
    Top Product
    Discover our top product HOMER1 Primärantikörper
  • Applikationshinweise
    WB: 1:500-1:2000, IP: 1:200-1:1000, IHC: 1:20-1:200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
    Haltbarkeit
    12 months
  • Target
    HOMER1 (Homer Homolog 1 (HOMER1))
    Andere Bezeichnung
    HOMER1 (HOMER1 Produkte)
    Hintergrund
    Synonyms:SYN47 Background:Postsynaptic density scaffolding protein. Binds and cross-links cytoplasmic regions of GRM1, GRM5, ITPR1, DNM3, RYR1, RYR2, SHANK1 and SHANK3. By physically linking GRM1 and GRM5 with ER-associated ITPR1 receptors, it aids the coupling of surface receptors to intracellular calcium release. May also couple GRM1 to PI3 kinase through its interaction with AGAP2. Isoform 1 regulates the trafficking and surface expression of GRM5. Isoform 3 acts as a natural dominant negative, in dynamic competition with constitutively expressed isoform 1 to regulate synaptic metabotropic glutamate function. Isoform 3, may be involved in the structural changes that occur at synapses during long-lasting neuronal plasticity and development.
    Molekulargewicht
    46-48 kDa
    Gen-ID
    9456
    UniProt
    Q86YM7
    Pathways
    Skeletal Muscle Fiber Development
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