GRB2 Antikörper
Kurzübersicht für GRB2 Antikörper (ABIN7114784)
Target
Alle GRB2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Verwendungszweck
- GRB2 antibody
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Aufreinigung
- Immunogen affinity purified
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Reinheit
- ≥95 % as determined by SDS-PAGE
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Immunogen
- growth factor receptor-bound protein 2
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Isotyp
- IgG
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Applikationshinweise
- WB: 1:500 - 1:2000, IHC: 1:50 - 1:200, IF: 1:10 - 1:100
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze / thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- -20°C for 12 months
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Haltbarkeit
- 12 months
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- GRB2 (Growth Factor Receptor-Bound Protein 2 (GRB2))
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Andere Bezeichnung
- GRB2
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Hintergrund
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Synonyms: Growth factor receptor-bound protein 2|Adapter protein GRB2|Protein Ash|SH2/SH3 adapter GRB2|GRB2|ASH
Background: The protein encoded by this gene binds the epidermal growth factor receptor and contains one SH2 domain and two SH3 domains. Its two SH3 domains direct complex formation with proline-rich regions of other proteins, and its SH2 domain binds tyrosine phosphorylated sequences. This gene is similar to the Sem5 gene of C.elegans, which is involved in the signal transduction pathway. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene.
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Molekulargewicht
- 33 kDa
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Gen-ID
- 2885
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UniProt
- P62993
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Pathways
- RTK Signalweg, T-Zell Rezeptor Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Regulation of Actin Filament Polymerization, Hepatitis C, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, EGFR Downregulation
Target
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