FBP1 Antikörper
Kurzübersicht für FBP1 Antikörper (ABIN7114350)
Target
Alle FBP1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Aufreinigung
- Immunogen affinity purified
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Reinheit
- ≥95 % as determined by SDS-PAGE
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Immunogen
- fructose-1,6-bisphosphatase 1
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Isotyp
- IgG
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Applikationshinweise
- WB: 1:5000-1:20000, IP: 1:500-1:1000, IHC: 1:100-1:400, IF: 1:50-1:500
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
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Haltbarkeit
- 12 months
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- FBP1 (Fructose-1,6-Bisphosphatase 1 (FBP1))
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Andere Bezeichnung
- FBP1
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Hintergrund
- Synonyms:FBP, FBP1, FBPase 1, fructose 1,6 bisphosphatase 1 Background:Catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate in the presence of divalent cations, acting as a rate-limiting enzyme in gluconeogenesis. Plays a role in regulating glucose sensing and insulin secretion of pancreatic beta-cells. Appears to modulate glycerol gluconeogenesis in liver. Important regulator of appetite and adiposity, increased expression of the protein in liver after nutrient excess increases circulating satiety hormones and reduces appetite-stimulating neuropeptides and thus seems to provide a feedback mechanism to limit weight gain.
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Molekulargewicht
- 37 kDa
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Gen-ID
- 2203
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UniProt
- P09467
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Pathways
- Cellular Glucan Metabolic Process, Regulation of Carbohydrate Metabolic Process, Dicarboxylic Acid Transport
Target
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