Fibrinogen beta Chain Antikörper (AA 150-491)

Produktnummer ABIN7114194

Dieses Anti-Fibrinogen beta Chain-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von Fibrinogen beta Chain in WB und ELISA. Geeignet für Human.

Kurzübersicht für Fibrinogen beta Chain Antikörper (AA 150-491) (ABIN7114194)

Target: Fibrinogen beta Chain (FGB)

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Fibrinogen beta Chain Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Klon: 6F4

Produktdetails anti-Fibrinogen beta Chain Antikörper

Bindungsspezifität: AA 150-491

Verwendungszweck: FGB antibody

Aufreinigung: Protein A+G purification

Reinheit: ≥95 % as determined by SDS-PAGE

Immunogen:

Immunogen sequence: 150-491aa

Immunogen: fibrinogen beta chain

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: WB: 1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C for 12 months

Haltbarkeit: 12 months

Details zu Fibrinogen beta Chain

Target: Fibrinogen beta Chain (FGB)

Andere Bezeichnung: FGB

Hintergrund:

Synonyms: Fibrinogen beta chain|Fibrinopeptide B|Fibrinogen beta chain|FGB

Background: Cleaved by the protease thrombin to yield monomers which, together with fibrinogen alpha(FGA) and fibrinogen gamma(FGG), polymerize to form an insoluble fibrin matrix. Fibrin has a major function in hemostasis as one of the primary components of blood clots. In addition, functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re-epithelialization. Was originally thought to be essential for platelet aggregation, based on in vitro studies using anticoagulated blood. However subsequent studies have shown that it is not absolutely required for thrombus formation in vivo. Enhances expression of SELP in activated platelets. Maternal fibrinogen is essential for successful pregnancy. Fibrin deposition is also associated with infection, where it protects against IFNG-mediated hemorrhage. May also facilitate the antibacterial immune response via both innate and T-cell mediated pathways.

Molekulargewicht: 50 kDa

Gen-ID: 2244

UniProt: P02675