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EPH Receptor A8 Antikörper

This anti-EPH Receptor A8 antibody (ABIN7113851) is a Rabbit Polyclonal antibody detecting EPH Receptor A8 in ELISA, WB. Suitable for Human, Mouse, Rat.
Produktnummer ABIN7113851

Kurzübersicht für EPH Receptor A8 Antikörper (ABIN7113851)

Target

Alle EPH Receptor A8 (EPHA8) Antikörper anzeigen
EPH Receptor A8 (EPHA8)

Reaktivität

Human, Maus, Ratte

Wirt

  • 7
  • 2
Kaninchen

Klonalität

  • 7
  • 2
Polyklonal

Konjugat

  • 5
  • 2
  • 1
  • 1
Dieser EPH Receptor A8 Antikörper ist unkonjugiert

Applikation

  • 7
  • 4
  • 1
  • 1
ELISA, Western Blotting (WB)
  • Aufreinigung

    Immunogen affinity purified

    Reinheit

    ≥95 % as determined by SDS-PAGE

    Immunogen

    EPH receptor A8

    Isotyp

    IgG
  • Applikationshinweise

    WB: 1:500-1:2000

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Buffer

    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

    Haltbarkeit

    12 months
  • Target

    EPH Receptor A8 (EPHA8)

    Andere Bezeichnung

    EPHA8

    Hintergrund

    Synonyms:EEK, HEK3, KIAA1459 Background:Receptor tyrosine kinase which binds promiscuously GPI-anchored ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. The GPI-anchored ephrin-A EFNA2, EFNA3, and EFNA5 are able to activate EPHA8 through phosphorylation. With EFNA5 may regulate integrin-mediated cell adhesion and migration on fibronectin substrate but also neurite outgrowth. During development of the nervous system plays also a role in axon guidance. Downstream effectors of the EPHA8 signaling pathway include FYN which promotes cell adhesion upon activation by EPHA8 and the MAP kinases in the stimulation of neurite outgrowth(By similarity).

    Molekulargewicht

    120 kDa

    Gen-ID

    2046

    UniProt

    P29322

    Pathways

    RTK Signalweg
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