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DNMT3A Antikörper

DNMT3A Reaktivität: Human, Maus, Ratte WB, ELISA, IP Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7113542
  • Target Alle DNMT3A Antikörper anzeigen
    DNMT3A (DNA (Cytosine-5-)-Methyltransferase 3 alpha (DNMT3A))
    Reaktivität
    • 122
    • 48
    • 47
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 114
    • 10
    Kaninchen
    Klonalität
    • 106
    • 18
    Polyklonal
    Konjugat
    • 51
    • 11
    • 10
    • 10
    • 8
    • 6
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser DNMT3A Antikörper ist unkonjugiert
    Applikation
    • 94
    • 59
    • 30
    • 27
    • 26
    • 16
    • 10
    • 8
    • 6
    • 6
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunoprecipitation (IP)
    Aufreinigung
    Immunogen affinity purified
    Reinheit
    ≥95 % as determined by SDS-PAGE
    Immunogen
    DNA(cytosine-5-)-methyltransferase 3 alpha
    Isotyp
    IgG
    Top Product
    Discover our top product DNMT3A Primärantikörper
  • Applikationshinweise
    WB: 1:500-1:2000, IP: 1:200-1:2000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
    Haltbarkeit
    12 months
  • Target
    DNMT3A (DNA (Cytosine-5-)-Methyltransferase 3 alpha (DNMT3A))
    Andere Bezeichnung
    DNMT3A (DNMT3A Produkte)
    Synonyme
    DNMT3A antikoerper, DNMT3A2 antikoerper, M.HsaIIIA antikoerper, MmuIIIA antikoerper, dnmt3a1 antikoerper, dnmt6 antikoerper, DNA methyltransferase 3 alpha antikoerper, DNA methyltransferase 3A antikoerper, DNA (cytosine-5-)-methyltransferase 3 alpha b antikoerper, DNMT3A antikoerper, Dnmt3a antikoerper, dnmt3a antikoerper, dnmt3ab antikoerper
    Hintergrund
    Synonyms: Background:Required for genome-wide de novo methylation and is essential for the establishment of DNA methylation patterns during development. DNA methylation is coordinated with methylation of histones. It modifies DNA in a non-processive manner and also methylates non-CpG sites. May preferentially methylate DNA linker between 2 nucleosomal cores and is inhibited by histone H1. Plays a role in paternal and maternal imprinting. Required for methylation of most imprinted loci in germ cells. Acts as a transcriptional corepressor for ZBTB18. Recruited to trimethylated 'Lys-36' of histone H3(H3K36me3) sites. Can actively repress transcription through the recruitment of HDAC activity.
    Gen-ID
    1788
    UniProt
    Q9Y6K1
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